D10, an activated collectible that turns all of the monsters in a room into different ones. ![]() D8, an activated collectible that re-rolls Isaac's speed, range, tears, and damage.D7, an activated collectible that restarts the room and respawns all monsters.Eternal D6, an activated collectible that has the same effect as the D6, but with a much shorter recharge and a chance to make the items disappear instead.The D6, an activated collectible that replaces every pedestal item in the current room (not pickups or trinkets) with other random items corresponding to the current room's item pool.from the pool where the item it replaces was acquired. D4, an activated collectible that re-rolls each of Isaac's items into a random item from the Treasure Room item pool.D1, an activated collectible that duplicates 1 random pickup, trinket, or chest in the current room.
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